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FIGURE 2 4.2 Probiotic and prebiotic modulation Probiotics and prebiotics, as key modulators of the gut microbiota, have shown potential in ameliorating symptoms of ASD (Liu et al., 2022

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weight-loss pharmacotherapy may not be appropriate Gastrointestinal conditions, particularly gastroparesis or inflammatory bowel disease Thyroid disorders (report any symptoms such as neck swelling, difficulty swallowing, or hoarseness) Diabetes and current glycaemic control Cardiovascular conditions Any history of pancreatitis or gallbladder disease All current medications and supplements must be disclosed, as both Wegovy and escitalopram may interact with other medicines

Neuron 54 , 801812 (2007)

It may be relevant when remodeling occurs under metabolic strain, including GLP-1 use, caloric deficit, chronic fatigue, or age-related NAD+ decline

Cool compresses can soothe localized irritation at injection sites