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PMID: 34828920

first-ever generic GLP-1 receptor agonist approved for weight loss in the U.S., representing a major milestone in making weight loss medications more accessible

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Moreover, GLP-1RA and DPP-4 inhibitors are approved for the treatment of T2DM and exhibit potential pleiotropic effects on the heart and kidneys, which may be independent of or dependent on the hypoglycemic effects

Some clinics prescribe GLP-1 medications off-label for things like: This off-label use may happen in the US and is controversial

This treatment is especially helpful for older adults and those following a vegetarian or vegan diet with limited natural sources