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A balanced microbiome is essential for keeping the lower esophageal sphincter functioning properly and preventing gas buildup that can push acid upward

Specifically, BDNF was necessary for differentiation but not the proliferation of newborn neurons, as the only difference between BDNF knockdown and controls was the number of cells expressing both proliferation marker (BrdU) and immature neuronal marker (DCX), whereas the total number of proliferating cells, either 24 h (Figure 5b) or 7 days (Figure 5c) after BrdU injections, was unchanged

Soldatos CR, Dikeos DG, Paparrigopoulos TJ

In colitis models, the peptide significantly reduced inflammatory markers and macroscopic damage signs

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