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Notably, certain anticancer treatments can cause a rapid rise in blood pressure, potentially worsening pre-existing cardiovascular conditions and, in severe cases, leading to acute hypertension-related complications [27]

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In 537 adults with type 2 diabetes (85% treatment-naive, on stable metformin), the 12mg dose produced HbA1c reductions up to 2.0% and weight loss up to 16.8% at 40 weeks, with no plateau observed

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