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In a review conducted by Mumme and Stonehouse (2015), randomized clinical studies with a minimum ingestion duration of 3 weeks were selected and analyzed

In the end, numerous clinical studies and controlled clinical trials on the assessment of the effectiveness of these novel topical formulations in melasma management are summarized

The exact mechanisms by which LD proteins are targeted for proteasomal degradation remain unclear

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Further, the assay is affected by pH, salt concentration, temperature, kind of buffer, and contaminants that may be present in the cuvette