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Use of Melatonin on Prematurity Melatonin has antioxidant effects, such as scavenging free radicals and enhancing antioxidant mechanisms, as well as anti-inflammatory effects, which can be beneficial in preventing PTB [113]

Cognitive reserve in ageing and Alzheimer's disease

10.1146/annurev-physiol-031522-021457 27 KuhnV.DiederichL.KellerT

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One of the mechanisms by which spermidine exerts anti-aging effects is through activation of autophagy

In addition, brain tumors are known to have disrupted BBB due to the tumor vasculature becoming increasingly heterogeneous as the tumor grows (203)