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This article examines the mechanisms, timeline, and factors influencing semaglutide's appetite-suppressing effects

Second, metabolic/bariatric surgery has been proven to be the most effective treatment in terms of weight loss and improvement in all associated comorbidities

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In addition to weight loss, some GLP-1 medications can reduce cardiovascular risk and help treat conditions such as fatty liver disease and obstructive sleep apnea

20 This observation emphasizes their potential to promote systemic metabolic health beyond glucose homeostasis and makes GLP-1RAs a more suitable treatment option for T2D patients with a higher risk of cardiovascular disease compared to metformin

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