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These mice were bred with Pomc-cre/, fNR1+/+ mice, and their Cre+/ offspring were used as DG-NR1KO mice and the Cre-negative littermates were used as controls

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After 4 h of incubation, green fluorescence was observed in cells cultured with FITC-labeled B2M-CuS NPs, whereas negligible fluorescence was observed in FITC-labeled CuS and control groups (Fig

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However, it is likely that CagriSema would need to be kept refrigerated between 2C and 8C (36F to 46F) when not in use to maintain its stability and efficacy