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These results imply that oligodendrocytes augment BBB integrity via pathways other than those involving platelet-derived growth factor receptor-BB/platelet-derived growth factor receptor signaling exerted by brain endothelial cell-secreted platelet-derived growth factor-BB [98]

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One such is the infusion of Vitamin C and glutathione

It does not involve the underlying skin pigmentation nor does it require exposure to ultraviolet light to initiate the color change