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Hypotheses 143:109862

The certainty of evidence, assessed using GRADE methodology, ranged from high for colorectal cancer to moderate for liver cancer to low for pancreatic cancer, reflecting variations in trial consistency and event rates ( Since most studies focused on liraglutide and semaglutide, the outcomes are most relevant to these drugs, even though the pooled analysis considered all data from the GLP-1 RA class

The coefficient of determination, R 2 , provides an estimate of the proportion of variance in the response variable explained by the model

PubMed, doi:10.1016/j.ejogrb.2014.02.036.Ahern, Thomas P., et al

Although GLP-1 medications help reduce hunger and cravings, the best results occur when treatment is combined with healthy eating, regular physical activity, and positive lifestyle habits

Li Y, Liu X, Yu J, Li Z, Chen Y, Li H, et al