Tucker, K
At the same concentration of 580 M, Cu(OAc) 2 induced a higher upregulation of IL1A than CuCl 2 , while CuCl 2 induced a higher upregulation of IL8, HSPA1A and FOSL1 than Cu(OAc) 2
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Mechanistic work probing how the Aib substitution at position 8 contributes to DPP-4 resistance compared with native GLP-1, where targeted residue substitution can be examined for its effect on enzymatic stability and receptor engagement