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POSSIBLE SIDE EFFECTS Low Blood Sugar (Hypoglycemia): Particularly when taken with other diabetes medications like sulfonylurea or insulin Gastrointestinal Issues: Such as nausea, vomiting, diarrhea, or stomach pain Eye Problems: Diabetic retinopathy might worsen with fast improvements in blood sugar control A complete list of side effects can be found in the product monograph referenced at the bottom of this page WHEN TO CONTACT YOUR DOCTOR OTHER INTERACTIONS With Other Medicines: Rybelsus may interact with other medications, so always inform your doctor about all the drugs you are taking