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The deficiency may be the result of reduced dietary intake, but a more likely explanation is as we age there is reduced secretion of a compound known as intrinsic factor that facilitates B12 absorption

Involvement of lipophagy and chaperone-mediated autophagy in the pathogenesis of non-alcoholic fatty liver disease by regulation of lipid droplets

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In chronic illnesses, mitochondrial function can become impaired, leading to further fatigue and reduced energy levels

doi: 10.1038/s41556-024-01507-7 55 YangMWeiXYiXJiangD-S