Coupled with the absence of clinical outcome measures and human clinical trial evidence, their direct clinical translation is restricted, highlighting an urgent need for more clinically relevant studies to optimize intervention strategies and clarify the actual therapeutic value of iron chelators in DR patients
Similar content being viewed by others 1 Introduction Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder affecting, most notably, both upper and lower motor neurons in the brain, brainstem, and spinal cord, leading to progressive weakness of limbs and bulbar muscles as well as neuromuscular respiratory failure [1]
Lipid peroxidation and glutathione peroxidase activity relationship in breast cancer depends on functional polymorphism of GPX1
These altered BAs profiles may subsequently affect the composition of the gut microbiota, thereby interfering with neural function and contributing to the development and progression of SZ
Zhang K, et al
Chlorophenothiazine exhibited direct antioxidant actions in mitochondria lysate assay compared to MB, which required reduction by NADH and mitochondria