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R.HeimburgerO.StenvinkelP.LindL.LarssonA.et al (2016)

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Nat Chem Biol, 2015

Research supports the long-term safety of creatine supplementation in healthy individuals

Trained men who exercised to exhaustion on a treadmill had increased blood amounts of oxidized glutathione immediately after exercise, suggesting an increase in oxidative stress, but returned to rest after 1 h

These are relatively small changes that the mucosa can handle thanks to its regenerative abilities