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Recovery and Tissue Repair Applications Beyond muscle building, IGF-1 DES has been investigated for localized tissue repair including accelerated healing of muscle injuries, potential benefits for tendon/ligament repair through collagen synthesis, enhanced recovery from localized trauma, and possible applications in wound healing
References Cell Metabolism (2015) The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance (Lee C, Zeng J, Drew BG, et al.) Journal of Translational Medicine (2023) Mitochondria-derived peptide MOTS-c: effects and mechanisms related to stress, metabolism and aging (Wan W, Zhang L, Lin Y, et al.) Journal of Molecular Medicine (2019) MOTS-c peptide regulates adipose homeostasis to prevent ovariectomy-induced metabolic dysfunction (Lu H, Wei M, Zhai Y, et al.) Nature Communications (2021) MOTS-c is an exercise-induced mitochondrial-encoded regulator of age-dependent physical decline and muscle homeostasis (Reynolds JC, Lai RW, Woodhead JST, et al.) Frontiers in Physiology (2023) Role of MOTS-c in the regulation of bone metabolism (Yi X, Hu G, Yang Y, et al.)
The ferroptosis inducer erastin irreversibly inhibits system x c - and synergizes with cisplatin to increase cisplatin's cytotoxicity in cancer cells
This condition, characterized by dark patches on the skin, occurs when melanin is produced in excess
And powerful biology sometimes creates powerful responses
