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GLP-1 RAs did not improve the change in LVEF (mean difference [MD]): 0.86, p = 0.12, left-ventricular end-diastolic volume (LVEDV) (MD: 3.54, p = 0.11), left-ventricular end-systolic volume (LVESV) (MD: 2.78, p = 0.07) or N-terminal pro-B-type natriuretic peptide (NT-proBNP) (MD: 140.36, p = 0.08)

The damaging effects of proinflammatory CK were described and characterized in rat [66] or cARLA treated human BBB models [40]

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PMID: 27742618, PMCID: PMC5121496, DOI: 10.1161/jaha.116.003923

Those with a BMI between 27.5 and 29.9 may qualify if they also have obesity-related conditions