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Radioactivity was measured with the TopCount scintillation counter (Perkin Elmer)
GSTs also have important roles in metabolism, such as signaling-ligand biosynthesis, tyrosine depredation, peroxide breakdown, and dehydroascorbate reduction
However, these are indicated only for acute exposure, and acetazolamide presents adverse effects such as paresthesia, dysgeusia, hyperglycemia, and rebound symptoms, limiting its long-term use ( Consequently, studies have evaluated antioxidant compounds such as vitamins C and E, -lipoic acid, and more recently standardized Ginkgo biloba extract, which has been attributed to potential antioxidant effects
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