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Proc Natl Acad Sci USA 114:31863191 Gonfloni S, Di Tella L, Caldarola S, Cannata SM, Klinger FG, Di Bartolomeo C, Mattei M, Candi E, De Felici M, Melino G et al (2009) Inhibition of the c-Abl-TAp63 pathway protects mouse oocytes from chemotherapy-induced death

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This selectivity stems from the unique dependence of senescent cells on the FOXO4-p53 interaction for survival, a vulnerability not present in proliferating or quiescent healthy cells

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