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[1] Why Glutathione Levels Decline With Aging Like many biological molecules, glutathione levels decrease as people get older

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Increased risk of low blood sugar, particularly if used along with insulin or an insulin secretagogue

During a two-year follow-up, 5,037 patients taking a GLP-1 developed diabetic retinopathy, compared with 4,938 who were not a 7% increased risk