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Here's why: Protecting Against Oxidative Stress: Oxidative stress has been linked to various pregnancy complications, including preeclampsia and gestational diabetes

[DOI] [PMC free article] [PubMed] [Google Scholar] 32.Kim E., Liu N.-C., Yu I.-C., Lin H.-Y., Lee Y.-F., Sparks J.D., Chen L.-M., Chang C

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Interestingly, bioinformatic analyses conducted on bulk tissue data obtained from healthy human brain tissue donors revealed that endothelial cells and microglia were the predominant senescent cell types, driven by CDKN1A/p21WAF1/CIP1 (42) revealing potential differences in senescent cell types between healthy and diseased states

We have included substrate activation (the Hill term on the right) and found that if we omitted this substrate activation then the cytochrome oxidase reactions did not produce enough NAPQI at high overdoses