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Six participants cannot define a treatment effect A crossover design can be useful for exploratory research, but a study involving six people cannot establish uncommon risks, long-term effectiveness or suitability for people with different health conditions

For those who suffer from a vitamin B12 deficiency, injections will likely be recommended every 10 days as a build-up phase and then will continue as a monthly treatment or to be administered every 2 to 3 months in order to completely reverse the side effects of the deficiency

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Accessed 26 Nov 2016

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In patients with no apparent cause of gynaecomastia, laboratory tests may be useful