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Mechanism 3: ROS Scavenging and MITF Suppression UV radiation generates reactive oxygen species that activate the Microphthalmia-associated Transcription Factor (MITF), the primary transcriptional regulator of tyrosinase gene expression

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Body Composition Body composition was measured in mice fed ad libitum at 10-11 weeks of age using an EchoMRI-100 TM Body Composition Analyzer (EchoMRI LLC, Houston, TX)

Aggregation Under certain conditions, individual peptide molecules associate with each other to form dimers, oligomers, and eventually larger aggregates

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doi: 10.3390/ijms20153611 275 KotwasIMcGonigalABastien-ToniazzoMBartolomeiFMicoulaud-FranchiJA