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[55] Hiles RA, Bawdon RE, Petrella EM

GLP-1 is a hormone that's released from the intestine in response to food intake and has a powerful effect on regulating different processes in the brain and body

However, fibromyalgia pain is centralizeddriven by amplified pain signal processing rather than joint damage alone

Beyond glycemic control, large outcome studies have confirmed that certain GLP-1 agonists significantly improve cardiovascular outcomes (reducing heart attacks, stroke, or cardiovascular death) in high-risk diabetic patients ( [8] ) ( [9] )

The new 5-HT hypothesis of depression: cell-mediated immune activation induces indoleamine 2,3-dioxygenase, which leads to lower plasma tryptophan and an increased synthesis of detrimental tryptophan catabolites (TRYCATs), both of which contribute to the onset of depression