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This initial phase corresponds with the dose escalation period, during which the medication dose increases every four weeks to enhance efficacy while maintaining tolerability

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Fixed-dose drug combinations In recent years, combination options involving two drugs in a single tablet have been incorporated into DM2 therapy in order to simplify the treatment regimen and thus improve patient adherence

Some women during the loading phase report excess bloating and water weight, which often subsides with continued use (Smith-Ryan et al., 2021)

Ethical statement The patient provided written informed consent for the case details to be published

Peng, J., Yuan, J