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Available at: [accessed March 2026]. Lincoff AM, et al

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Research findings point to the capacity of busulfan to induce cellular senescence in various cell types, including mesenchymal stem cells, fibroblasts, and the cell lines of human osteosarcoma cells U2OS and MG63 [65,66,67]

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Activation of MC1R in melanocytes stimulates eumelanin production, leading to pigmentation