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In a yearlong Phase 3 trial, the highest dose of Lilys pill, orforglipron, lowered a measure of blood sugar called A1C by 1.9 percentage points, while the highest dose of Novos drug, marketed as Rybelsus, lowered A1C by 1.5 percentage points, when analyzing all patients regardless of discontinuations

Also, compared to those who were in the placebo group, those who received 2.4 mg of semaglutide were more likely to lose 5% or more of body weight at 68 weeks

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For example: Extremely sensitive patients may only need 100mg per day

People who've struggled with their weight for years can feel a huge initial boost when the pounds come off