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Absorption of the His-tagged protein is performed at neutral to slightly alkaline pH to prevent protonation and loss of binding capacity of the weakly basic histidine imidazole groups

Dietary tyrosine supplement increases plasma tyrosine (A), which inturn increases CSF tyrosine (B)

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Magnesium works through osmotic mechanisms

Pharmacol Biochem Behav 46 : 423426 Moreau JL, Jenck F, Martin JR, Mortas P, Haefely WE

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