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6 The phase 2 monotherapy dose-finding trial by Lau and colleagues established that once-weekly cagrilintide up to 4.5 mg produced dose-dependent weight loss about 10.8% at the top dose over 26 weeks with a gastrointestinal side-effect profile (nausea and related symptoms) that is the clinical fingerprint of a gut-slowing, satiating mechanism

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Strong local, not global, controls on marine pyrite sulfur isotopes

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The researchers also noted that areas of the brain with higher glutathione concentrations are more resilient to the aging process, explaining the better memory and learning outcomes

Bouayed J, Bohn T