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Combined naltrexone-semaglutide therapy amplifies gastrointestinal side effects (nausea, vomiting, constipation), increases fatigue risk, and may lower seizure thresholds

Utilization Management Call Center Authorization requests are submitted through our provider portal at www.jeffersonhealthplans.com/providers/provider-portal

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Post hoc comparisons, adjusted for multiple comparisons by Bonferronis correction, were performed if the ANOVAs showed a significant interaction between treatment and time

Pancreatitis : An association between GLP-1-based therapies and acute pancreatitis has been observed, though a definitive causal relationship has not been established