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Then a rigorous Phase 3 trial of exenatide found no benefit over placebo, failing to slow progression in the largest and longest study of its kind

In some countries, this has led to severe drug shortages and challenges for the diabetic population

The first and only FDA-approved semaglutide pill for weight loss in adults with obesity or overweight with a weight-related condition

Semaglutide helps people lose significant weight, sometimes 50 to 100 pounds or more

Talk to your provider: You may need a dosage change, a different GLP-1, or additional support