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The Lancet , 350(9080), 566568
de Oliveira, S
In AD lesions, Th2 cytokines such as IL-4 and IL-13 are chronically secreted, and these cytokines commonly activate the transcription factor signal transducer and activator of transcription 6 (STAT6) (Heckert et al
Additionally, N-acetyl cysteine (NAC) is often used as a precursor
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( B ) Under conditions of APAP overdose along with iron overload, the excessive cellular free iron reacts with mitochondrial reactive oxygen species (ROS) to induce lipid peroxidation (LPO) of membranes
