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Brain research, 583(1-2), 194200.

The importance of this hinge region was confirmed by the synthesis and utilization of a hexapeptide mimic (Hinge: KDYIRN) that bound to HGF with high affinity and blocked HGF dimerization [38]

2007Phase 2, placebo-controlled dose-escalation study of pramlintide in non-diabetic obesity

This trial focuses on obesity in adults with type 2 diabetes, addressing the critical question of how retatrutide performs when glycemic control is a co-primary endpoint alongside weight loss

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