Clinicians avoid combining therapy with dipeptidyl peptidase-4 inhibitors due to minimal glycemic benefits and increased hypoglycemic risk (30)
In this study, the difference in body weight reduction between tirzepatide- and semaglutide-treated groups can only partly explain the improvement in insulin sensitivity, lending support to the observation that tirzepatide was associated with improvements in insulin sensitivity associated with both body weight-lowering and a potential insulin-sensitizing effects of GIP
Its expensive, often difficult to get due to shortages, and still relatively new, meaning its long-term effects arent as well understood
Consult your doctor or team care before making any changes.
Administration Should be taken with food: Take w/ or immediately after meals
Always consult with a healthcare provider before beginning any supplement regimen, especially if pregnant, nursing, or on medication