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For patients in South Florida, the heat outside the refrigerator is an especially important factor: a peptide vial left on a counter in a Doral kitchen during summer is exposed to ambient temperatures that can reach the mid-80s Fahrenheit or higher, which meaningfully accelerates degradation for any reconstituted solution left out during injection preparation

Never return a room-temperature-exposed vial to refrigerated storage for later use

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It appears to activate the ghrelin receptors (GHSR) which appear to trigger growth hormone synthesis

doi: 10.2337/db07-1056

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