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doi:10.1053/j.jvca.2019.07.147 Spencer-Segal JL, Hyzy RC, Iwashyna TJ, Standiford TJ

These side effects were usually mild or moderate, often improved with time, and only a small number of participants stopped treatment because of them

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In contrast, under antioxidant/low-ROS conditions (such as in certain tumor microenvironments or after treatment with BPC157 in our study), BACH1 becomes stabilized and can switch to promoting angiogenesis by directly activating target genes like VEGF

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