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The BUD is typically more conservative than a traditional expiration date because compounded medications have not undergone the extensive stability testing that commercial products require

Updated Phase 3 data from December 2025 (TRIUMPH-4 trial) pushed those numbers even higher, with the 12mg dose delivering 28.7% weight loss at 68 weeks, which works out to approximately 71 lb lost on average

Professional bodies like The Obesity Society and endocrine societies recommend considering medications like Saxenda or Wegovy for patients with BMI 30 (or 27 with comorbidities) who have not achieved weight loss goals with lifestyle changes alone ( [145] ) ( [146] )

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January 2026: Novo Nordisk A/S reported record prescriptions for Ozempic, Wegovy, and Rybelsus, launching enhanced digital support tools for patient adherence and weight tracking