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Ahmed A, Saleem MA, Saeed F, et al

A further subgroup analysis was performed only for body weight parameters (that is, TBWL%, waist circumference, BMI and proportion of patients achieving at least 5%, 10%, 15%, 20% and 25% of body weight reduction) in RCTs specifically designed for body weight reduction

However, noticeable effects like improved sleep typically appear within 1-2 weeks, while body composition changes usually become apparent around weeks 6-8

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