Potential therapeutic role for treatment of gastroparesis Owing to its effects on gastric motility and appetite regulation, researchers have explored the potential therapeutic use of GLP-1 receptor agonists in the context of gastroparesis
High-Dose Oral Supplements For individuals without issues absorbing B12 from their gut, high-dose oral supplements can be surprisingly effective
Suchankova P, Yan J, Schwandt ML, Stangl BL, Caparelli EC, Momenan R, et al
Other contraindications and precautions for GLP-1 agonists include a history of severe allergic reactions to the medication or its components, acute or chronic pancreatitis, gallbladder disease or gallstones, and certain forms of diabetic retinopathy
The safety assessment is based on the independent safety profiles of each compound (GLP-1 medications through extensive FDA trials, BPC-157 through decades of preclinical research), their non-overlapping mechanisms, and growing clinical experience from physicians who prescribe both
[75] Anxiolytics (CNS depressants such as benzodiazepines and barbiturates): Kava may have potential additive CNS depressant effects (such as sedation and anxiolytic effects) with benzodiazepines and barbiturates