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Stahl quote: "Follow the FDA label and never get anybody better" [22:10] When GLP-1s aren't appropriate [24:01] Case study: patient on paliperidone gaining weight despite tirzepatide [25:52] Discovery of nucleus tractus solitaris [28:26] The "are we allowed to prescribe this?" debate [29:10] Valproic acid, propranolol, and scope of practice [30:01] Bipolar disorder, obesity, and mood episode frequency [30:49] Moving beyond the monoamine hypothesis [31:19] UK paper: no proof depression is serotonin deficiency [33:23] Alternative treatments: TMS, ketamine, GLP-1s [34:03] Dr
Current MHRA guidance and NICE protocols emphasize that while GLP-1 receptor agonists offer transformative potential, they must be managed with precision
Always consult your doctor before changing how you take your meds
Liraglutide, the most extensively studied drug, consistently reduced both amyloidbeta and tau pathology
Anthony MR et al
