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Glucagon also contributes to energy homeostasis by promoting satiety through vagal signaling to brainstem nuclei and by increasing resting energy expenditure through facultative thermogenesis in brown adipose tissue, skeletal muscle, and through promotion of WAT browning [22]

doi:10.1172/JCI29444

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Backed by Clinical Research One of the largest menopause-focused studies on saffron involved 86 women aged 40 to 60 who took 28 mg of Affron saffron extract daily for 12 weeks