SUSTAIN-6 demonstrated a significant reduction in HbA1c levels and body weight compared to placebo, along with a reduction in cardiovascular risk
Neuroinflammation in turn, interferes with neuroplasticity by reducing neurogenesis, altering synaptic architecture, and dysregulating neurotransmitter systems [7,8], changes that are closely linked to mood disturbance, cognitive impairment, and affective lability in individuals with IR [4,6,9]
The good news is these medications, semaglutide, the active ingredient in Ozempic and Wegovy, or tirzepatide, the active ingredient in Mounjaro, are part of a class of medications, GLP-1 receptor agonists, that have been around for over 20 years so we know the side effects, mostly gastrointestinal in nature (nausea, vomiting, constipation and diarrhea)
Her story is complemented by science-based nutritional guidance, developed in collaboration with registered dietitian Melissa Mitri, ensuring the credibility and scientific basis of the advice
doi:10.3233/JAD-150777 Jerneren F, Elshorbagy AK, Oulhaj A, Smith SM, Refsum H, Smith AD
However, when you lose weight rapidly, you inevitably lose some muscle , which further lowers your metabolic rate
