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It is a macrolide-type antibiotic

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This cycle is activated by the combination of glutathione depletion, which increases the activity of -glutamyl cysteine synthetase, and cysteine deficiency, which prevents the high energy intermediate product -glutamyl phosphate (step 1) from being converted to -glutamyl cysteine (step 2)

The risk of being in a crash begins to rise between .04% and .05% BAC, and increases rapidly thereafter

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