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Radiolabeled exendin-4 derivatives, such as 68 Ga-NOTA-exendin-4 and 18 F-PEG-exendin-4, have significantly enhanced the sensitivity and specificity of insulinoma detection via PET/CT, outperforming conventional imaging modalities [346350]

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Oxygen can slowly seep into the vial, leading to oxidation

This interaction can temporarily alter energy levels and contribute to feelings of fatigue

[168] [169] In June 2025, the European Medicines Agency recommended that the product information for semaglutide medicines be updated to include non-arteritic anterior ischemic optic neuropathy (NAION) as a very rare side effect, [170] while the World Health Organization concluded that the risk management plan for semaglutide should be revised to include NAION as a potential risk

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