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This peptide, which he named exendin-4 , was approximately 53% identical in amino acid sequence to human GLP-1, but with one critical difference: while human GLP-1 is degraded by an enzyme called DPP-4 within minutes of being released, exendin-4 was resistant to that breakdown

M., Bugianesi, E., Rinella, M

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Proc Natl Acad Sci U S A 2020;117:2995967.PubMedPMC 39