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Selon ltat du stress oxydatif cellulaire, on peut retrouver le Glutathion sous deux formes : l tat rduit, ou GSH , et l tat oxyd, ou GSSG

In addition to redox imbalance, aging oocytes exhibit progressive genomic instability, deterioration of chromosome cohesion, and reduced efficiency of the spindle assembly checkpoint, all of which increase the risk of meiotic errors and aneuploidy

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