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Athletes should consult an endocrinologist to avoid supraphysiologic GH levels that could suppress the HPT axis

Wegovy and other weight loss injections, like Mounjaro, can allow you to make lifestyle changes to support long-term weight loss

A major challenge in MSTN inhibition is the potential for off-target effects, as other TGF- family ligands, such as GDF11, activins, and BMPs, share the same receptor.[81] Thus, blocking MSTN may unintentionally disrupt other critical signaling pathways

Remember that it takes time for your body to get used to the medication, and significant weight loss is typically realized over the long term once your dose is increased

35 The Wnt/-catenin pathway, essential for bone formation, also affects adipose tissue fibrosis and energy metabolism, illustrating how bone-targeted interventions may lead to unexpected systemic consequences