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Briefly, Mercury(II) ions present in the environment cross the microorganisms cellular membrane and are scavenged by MerA, a homo-dimeric enzyme which sandwiches the Hg 2+ between a pair of catalytically essential cysteine thiol groups, to make a protein-embedded mercury(II)-bis-thiolate

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Regulation of cellular glucose uptake The binding of insulin to the insulin receptor stimulates a cascade of protein phosphorylations leading to the translocation of glucose transporters (GLUT4) to the cell membrane and an increased cellular uptake of glucose (3, 42)

By 1997, Ng and colleagues had identified the C-terminal segment of human GH as the primary region governing fat metabolism, and created AOD 9604 by adding a tyrosine residue to the fragment to enhance its stability

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