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It is a GLP-1 agonist that is the first one in the class to have an oral formulation
At the end of the three-month study, both groups had a significant reduction in Leeds assessment of neuropathic symptoms and signs (LANSS) and Douleur Neuropathique (DN4) scores, but there was no significant difference between groups [39,40]
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Patients who experience nausea or other gastrointestinal symptoms at standard starter doses often tolerate low-dose protocols better, which can improve adherence and long-term outcomes
J Control Release 348:115126 Liu Z, Bu R, Zhao L, Liu L, Dong N et al (2021) Hydrogel-containing PLGA microspheres of palonosetron hydrochloride for achieving dual-depot sustained release
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