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Bariatric surgery is effective, but is only used in severe obesity due to risk of surgical complications [33], therefore alternative therapies with improved efficacy and low risk of side effects are of great interest

For patients with one kidney and stable renal function, oral formulations may work, but injectables offer superior control

These isoforms are involved in controlling intracellular redox signaling for the cellular processes of apoptosis and proliferation [17,18]

Clinical trials have shown that canagliflozin reduces major adverse cardiovascular events (MACE) [15], while empagliflozin decreases cardiovascular mortality by 38% and heart failure hospitalizations by 32% in patients with T2DM at high cardiovascular risk [16]

Impact of loop diuretic on outcomes in patients with heart failure and reduced ejection fraction

Red algal sulfated galactan binds and protects neural cells from HIV-1 gp120 and Tat